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DNA sequence detection according to given format

$10-30 USD

Closed
Posted almost 7 years ago

$10-30 USD

Paid on delivery
Please use Python3 for the following questions involving programming. 1. Analyze the code given in [login to view URL] and please add appropriate documentation. 2. Write the contents of function Site_finder(full_seq, subseq) in [login to view URL] along with a set of unit tests. 3. Write a search function to satisfy a given set of criteria (described below). Please include documentation and test code. DNA sequences are comprised of A, T, G, and C letters only. DNA letters are called ‘nucleotides’. The letter ‘N’ refers to any nucleotide, and the letter ‘R’ refers to G or A only. (How many unique sequences are described by the ‘GNRA’ motif?) The term ‘complementary’ refers to the pairings A:T and G:C such that the following sequences are complementary: ATCG |||| TAGC A single strand of DNA can fold. If folding occurs, a stable hairpin-like structure can form if enough complementary nucleotides exist in the appropriate locations. For example, the string ‘ATTCGGTAACGCAT’, representing a single strand of DNA, can fold up to form the following hairpin structure: T A G A G-C C-G T C T-A seq_start - A-T - seq_end The “loop region” is shown in bold font and the “stem region” is colored grey. The stem region is also referred to as a ‘complementarity region’. Complementary nucleotides in a stem region are said to be ‘paired’ with each other. Pairing interactions between complementary nucleotides are indicated by the ‘-’. In this task, you are to find and output all substrings of a DNA sequence given the following set of rules. Note that the example 14 NT sequence shown above matches the below criteria. Rule 1: substring length >= 12 and <=100 Rule 2: A ‘GNRA’ motif is at the center of the subsequence Rule 3: The subsequence contains at least 4 pairs of complementary nucleotides. Rule 4: Each half of each complementary pair must be located equidistant from the center of the ‘GNRA’ motif as shown in the diagram of the hairpin structure above. Rule 5: Both nucleotides of one of the complementary pairs must be a distance of <= 2 from either end of the ‘GNRA’ motif Rule 6: At least 70% of nucleotides in a complementarity region must be participating in a pairing interaction. The input sequence for this question is in “[login to view URL]”.
Project ID: 13899668

About the project

8 proposals
Remote project
Active 7 yrs ago

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8 freelancers are bidding on average $56 USD for this job
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Greetings sir, i am an expert freelancer for this job and your 100% satisfaction is assured if you allow me to serve. Here is the reason. Why you should pick me? a) I am a very expert and have the same kind of experience of 5 years. b) I work very hard (16+ hours a day and 7 days a week) and also very fast so... it will be done very soon than most of the other providers c) And most important part is my policy: "I will give you (to my client) life time support (as long as you keep relation with me). And fix any bugs/problem without any cost. So, don't ever worry about me” Please sir, leave a reply ASAP, as I am waiting for your kind reply
$100 USD in 1 day
5.0 (6 reviews)
4.3
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Have worked with dna assignments before and am a python tutor and developer.
$20 USD in 2 days
4.8 (5 reviews)
3.5
3.5
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Hi, I'm currently Gold level in USACO, the USA Computing Olympiad, which is a national algorithm competition. I have been studying algorithms for the past 2 years. I think I could finish your project pretty quick, depending on my school schedule. I can also help you understand the code, because I feel like this is a homework assignment :-) Feel free to DM me if you want to negotiate. Hope I can help you! Michael
$15 USD in 2 days
0.0 (0 reviews)
0.0
0.0
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Dear Prospect Hiring Manager. Thank you for giving me a chance to bid on your project. i am a serious bidder here and i have already worked on a similar project before and can deliver as u have mentioned I have checked your requirements. We have right skills to work on this assignment. We are a team of professionals including experienced analysts, designers, project managers, developers and QA people having great expertise in web applications development mainly on core PHP, PHP with open sources (Joomla, Wordpress, Codeigniter, Cake PHP), .NET, Asp.NET, Vb.NET, HTML 5 etc. and mobile applications on ios and Android platform. Our award = superb result = happy client. In a good partnership, good results happen. Good cooking makes good eating!BWe consider our client as our partner. I am ready to discuss with you with best Regards
$28 USD in 6 days
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Flag of UNITED STATES
Houston, United States
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Member since Feb 24, 2015

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