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salboni, india
It's currently 6:35 PM here
Joined June 3, 2018
1 Recommendation
Manjulata Devi S.
@Manjusundru
5.5
5.5
salboni, india
100%
Jobs Completed
79%
On Budget
97%
On Time
15%
Repeat Hire Rate
Scientist/ Biotechnologist/ Bioinformatician
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Portfolio Items
Immunomodulatory aspects of Probiotic Lactobacillus
Comparative genomics
DNA data analysis
Bioinformatics project
Scientific Research writer, proposal writing, content writer
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Experience
Young Scientist
Sep 2014 - Sep 2017 (3 years)
Worked as Young Scientist (Principle Investigator) under startup grant scheme sponsored by SERB-Department of Science and Technology (DST), New Delhi, India, with the project entitled “Detection and expression of immunomodulatory and probiotic marker genes among Lactobacillus sp.”
Research Associate
May 2013 - Jan 2014 (8 months, 1 day)
Worked as Project Assistant Level-IV (Research Associate) (16th May 2013 to 27th Jan 2014), in an Indian Council of Medical Research (ICMR) funded project entitled “Rapid detection of probiotic lactic acid bacteria and assessing their suitability In Vivo system”.
• Produced actionable information that improved the research data and published an article related to the project at "Probiotics and anti-microbial peptides journal".
Senior Research Fellow
Oct 2008 - Jul 2012 (3 years, 9 months)
Worked as a Ph.D Research Scholar with the Senior Research Fellowship (SRF) awarded by Council for Scientific and Industrial Research (CSIR), New Delhi.
Ph.D. Thesis title: Molecular genetic studies of pediocin-like bacteriocin in Pediococcus,
Lactobacillus and Enterococcus sp.”
Education
PhD, Biotechnology
(4 years)
Masters of Science, Microbiology
(2 years)
Bachelor of Science (Microbiology, Genetics, Chemistry)
(3 years)
Qualifications
Young Scientist Award
SERB- Department of Science and Technology, New Delhi
2014
PhD, Biotechnology
University of Mysore
2013
Publications
Discrimination and divergence among Lactobacillus....probiotic functionalities from vegetable origin
Systematic and Applied Microbiology
As determined by nucleotide sequence analysis and bioinformatics Pfam database, the putative
Fbp protein and Mub protein had shown variation. However,
L. pentosus, L. plantarum subsp. argentoratensis and L. arizonensis isolates gave no amplicon for the tested marker genes. Selected cultures showed tolerance to simulated digestive fluids (20–85%), exhibited auto-aggregation (10–77%), cellular hydrophobicity (12–78%), and broad spectrum of anti-microbial activity.
Diversity and evolutionary aspects of mucin binding (MucBP).....through comparative genetic analysis
Systematic and Applied Microbiology
Mucin binding protein (Mub) of Lactobacillus plantarum- group (LPG) is considered as a potential marker gene due to its diversity and adherence property to host intestinal layer. The mub gene expression pattern noted by real-time PCR revealed 67.64 increased fold change in MTCC 9483 with four MucBP repeats.Whereas, the isolates with 3 and 2 MucBP repeats showed ∼4 and 2 enhanced expression, respectively.
Genetic Variation of pln Loci Among Probiotic..... with Antioxidant and Cholesterol-Lowering Ability
Probiotics and Antimicrobial Proteins
In the present study, 14 different plantaricin encoding genes of pln loci were studied and compared to
available sequences from public domain database of probiotic Lactobacillus plantarum strains. Based upon the presence and absence of selected genes, pln locus was grouped into eight clusters. Further, quantitative real-time PCR (qRT-PCR) analysis for seven genes has discriminated the complex pln locus into five types which includes WCFS1, closely related to J51, J23, NC8, and a new E1 type.
In vitro anti-inflammatory activity among probiotic Lactobacillus species......
Journal of Functional Foods
Probiotic bacteria have the ability to alter immune response conferring treatment to inflammatory diseases. In
the current study, probiotic Lactobacillus strains were subjected to adhesion to epithelial Caco-2 cells.
Subsequently, gene expression of pro-and anti-inflammatory genes were studied under three stimulation.
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